SOBREVIVIR, RESISTIR Y LUCHAR. LAS COMUNISTAS DURANTE LA DéCADA DE LOS 80 EN CHILE


Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing

Osimertinib, which is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, is an important anticancer drug because of its high efficacy and excellent safety profile.However, resistance against osimertinib is inevitable; therefore, therapeutic strategies to overcome the resistance are needed.Doxazosin, a classic quinazoline

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